Common medications could delay brain injury recovery

first_imgLinkedIn Email Pinterest Share Share on Twittercenter_img Share on Facebook Drugs used to treat common complaints could delay the recovery of brain injury patients according to research led by University of East Anglia (UEA) scientists working with other UK universities including Aston and the NHS, published today in Brain Injury.Prescribed for up to 50 per cent of older people, medications with anticholinergic properties are used to treat a broad range of common conditions including bladder problems, depression and insomnia.Anticholinergics are already known to have side effects such as temporary cognitive impairment, dizziness and confusion. But their effects on people with pre-existing brain and spinal injuries have not been investigated until now. Medications with anti-cholinergic properties are often used on neuro-rehabilitation units frequently to manage symptoms from urinary incontinence to pain.The study of 52 patients with acquired brain or spinal injury at a neuro-rehabilitation unit showed that the average length of stay was longer in patients with a higher level of anticholinergic drugs in their system, known as the anticholinergic drug burden, or ACB.Results showed that the change in ACB correlated directly to the length of hospital stay. A higher ACB score on discharge, compared with on admission, was associated with a longer stay in hospital and a lower ACB on discharge saw on average a shorter stay. The team cautioned however that as an observational study, cause-and-effect relationship cannot be implied.Dr Chris Fox, Professor of Clinical Psychiatry at the Norwich Medical School at UEA and lead author on the paper, said: “The findings suggest there may be a statistically significant relationship between ACB score and length of stay in a neuro-rehabilitation unit following traumatic brain or spinal cord injury”.He added: “This pilot study demonstrates the need for larger studies to confirm the results and need for further investigation into what long-term effects these common medications are having on the recovery of these patients.”“While medications with ACB are often needed to treat common complications of brain or spinal cord injuries, cognitive impairment due to the medication may adversely affect a patient’s ability to engage in the rehabilitation process, potentially increasing their length of stay in hospital.”Length of patient stay is used a performance indicator for hospitals, with financial incentives in place for units to discharge patients as soon as is safe.Dr Ian Maidment, Senior Lecturer in Clinical Pharmacy at Aston University said: “This work adds to the evidence that anticholinergics should be avoided in a wide-range of populations, when possible. Regular medication review by a nurse, doctor or pharmacist may be a way of ensuring that medicines with anti-cholinergic effects are used appropriately.”Prof Fox said: “Identifying factors which might adversely affect the length of a patient’s stay can have important financial as well as quality of life implications. So the findings of this study could be directly useful to current health care settings if they can reduce the time patients spend in rehabilitation units, improving wider efficiency of care.”‘Does anticholinergics drug burden relate to global neuro-disability outcome measures and length of hospital stay?‘ is published in the journal Brain Injury on Monday 10 August 2015.last_img read more

People Moves: Lunson Michenall, Lee & Priestley, DPP and more…

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Tweed’s: Turn Of The Century Charm

first_imgA trip to Tweed’s, the steakhouse and buffalo bar in Riverhead, is a trip back in time. That’s not a cute euphemism, either. The building that houses the iconic Main Street restaurant, a brick façade with gas-lit lanterns, was erected in 1896 and has operated as the 14-room J.J. Sullivan Hotel ever since. Turn-of-the-century charm and details have been painstakingly restored to recall the space’s provenance. The hotel was originally built by Tammany Hall crony John J. Sullivan and became, necessarily, entrenched in American political history forever after.Known affectionately — or maybe not so affectionately — as the “Tammany Hall of the County Seat,” the restaurant and hotel have played host to many a political meal. If only the walls could talk. Above the restaurant, the rooms are small, though quaint and comfortable. The restaurant itself, outfitted with a mahogany bar from the 1893 Chicago World’s Fair, boasts time period-appropriate paraphernalia: Victorian light fixtures, an oak fireplace mantel recovered from a South Carolina mansion, armchairs, and various other bespoke artifacts.Wooden chairs with leather seats. The stuffed head of the final bison ever shot by Theodore Roosevelt. Ancient photographs of downtown Riverhead. History opens up in the dining room here.New York City politicians (most notably, the Democratic politician “Boss” Tweed, known for his cronyism) frequented Tweed’s, giving it caché, though eventually, like much of Riverhead, the restaurant fell into disrepair. In the early 2000s, Tweed’s underwent a renovation, including a restoration of the façade.But these days, politics play nearly no role in the iconic restaurant, which is now known for its superlative steaks and, yes, bison. A sprawling menu covers most bases. Raw bar? Check. Classic steakhouse Caesar salad? Check. A play on shrimp cocktail? You guessed it. In addition to red meat, entrées include Long Island duck, roasted chicken, seared tuna, baked salmon, veal chops, and Portobello mushrooms.And then, of course, there are the steaks.The list of beef and bison feels nearly endless. There is a hanger steak, served with a mushroom-Cognac cream sauce, and a filet mignon with a tarragon demi-glace. A grilled New York strip comes with crispy leeks. Prime rib? It’s here. There is a beef burger, of course, with cheese, onions, mushrooms, and bacon. There’s also a bison burger, offered with the same accouterment.As for bison, there is plenty to enjoy, from the appetizer of bison carpaccio to the grilled bison filet to the bison T-bone steak. But the most impressive dish on the menu is the hulking grilled bison cowboy steak, a cut I have never before seen from this animal. It is a massive, impressive thing, arriving on the bone and with an ample helping of maître d’ butter. Bison is leaner than beef, and the steak benefits from the melting fat of the butter (which can feel, atop a beef rib eye, like overkill, if such a thing exists).If this feels like not-enough-bison for your particular taste, you can opt to purchase more to bring home. The restaurant sells bison hanger steaks, filets, cowboy steaks, T-bones, and chop meat for those eager to try their hands at bison on the backyard grill. If dessert at a steakhouse often feels like an afterthought, think twice about skipping it at Tweed’s, where the crème brûlée is ever delicate and trapped beneath a thick disk of caramelized sugar. All steakhouse meals should end, I think, with a piece of inappropriately caloric chocolate cake, and Tweed’s takes its seriously enough. What’s the harm in a piece of cake, anyway? You can always take the rest home — assuming there’s anything left to save. Sharelast_img read more

Most read: 09.01.09

first_imgStay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to building.co.ukBreaking industry news as it happensBreaking, daily and weekly e-newsletters To continue enjoying Building.co.uk, sign up for free guest accessExisting subscriber? LOGIN Get your free guest access  SIGN UP TODAY Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our community Subscribe now for unlimited accesslast_img read more

Wouldn’t you like to live in the past?

first_imgTo continue enjoying Building.co.uk, sign up for free guest accessExisting subscriber? LOGIN Stay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to building.co.ukBreaking industry news as it happensBreaking, daily and weekly e-newsletters Subscribe now for unlimited access Get your free guest access  SIGN UP TODAY Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our communitylast_img read more

ADR: RSVP or face costs sanctions

first_imgTo continue enjoying Building.co.uk, sign up for free guest accessExisting subscriber? LOGIN Stay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to building.co.ukBreaking industry news as it happensBreaking, daily and weekly e-newsletters Get your free guest access  SIGN UP TODAY Subscribe now for unlimited access Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our communitylast_img read more

Pre-tax profits up at Air Partner

first_imgThe charter broker saw total revenues fall by 15 percent year-on-year to GBP102.1 million (USD154.1 million), although its pre-tax profits rose by 8 percent to GBP1.3 million (USD1.96 million). Freight brokering revenues for the half-year trading period reflected the loss of a large government contract, according to Air Partner, falling 56 percent over 2012 levels to GBP7.9 million (USD11.9 million). Profit before tax remained flat at GBP100,000 (USD150,920), however.The charter broker reports that it remains debt free and has cash reserves of GBP17.3 million (USD26.1 million). The company saw its strongest performance in the private jet sector where its revenues grew 12 percent year-on-year to GBP22.7 million (USD34.26 million). Air Partner added that its commercial jets division also progressed in tough trading conditions. “Difficult conditions continue to prevail, but despite the macroeconomic environment the Group has delivered profitable growth in line with our expectations,” commented Mark Briffa, ceo, Air Partner.  www.airpartner.comlast_img read more

Gov. Scott, Atty. Gen. Bondi land GOP convention spots

first_imgGov. Scott, Atty. Gen. Bondi land GOP convention spots CLEVELAND (AP) – There are war heroes, a casino mogul and even an underwear model, yet Donald Trump is relying heavily on his party’s establishment to fill the speaking program for next week’s Republican National Convention.The presumptive presidential nominee has approved a convention program that features at least 20 current or former elected officials, including Senate Majority Leader Mitch McConnell, House Speaker Paul Ryan and Texas Sen. Ted Cruz. Noticeably absent from a speaker list obtained by The Associated Press early Thursday are the athletes and A-List celebrities that Trump’s team long suggested would help make his presidential nominating convention unlike any other.The New York Times revealed a list on Twitter overnight that includes Florida Gov. Rick Scott and Attorney General Pam Bondi.We have the list of speakers at next week’s Republican convention https://t.co/kgIe35zr11 via @jwpetersnyt pic.twitter.com/mwH3vSFBrx— NYT Politics (@nytpolitics) July 14, 2016Still, there is no shortage of political outsiders.Speakers will include four of Trump’s children, Las Vegas casino owner Phil Ruffin, and actor and former underwear model Antonio Sabàto Jr. And in a slap at Democratic contender Hillary Clinton, Mark Geist and John Tiegen will also take the stage, both survivors of the deadly 2012 attack on the American diplomatic consulate in Benghazi, Libya.“This impressive lineup of veterans, political outsiders, faith leaders and those who know Donald Trump the best – his family and longtime friends – represent a cross-section of real people facing the same challenges as every American household,” said Trump spokesman Jason Miller.Despite the list of familiar politicos, the convention program is a reminder that the Republican Party remains deeply divided over Trump’s candidacy.Some of the GOP’s biggest names were not on the list because they refused to participate in four-day convention, which begins on Monday.The GOP’s two living presidents, George H.W. Bush and George W. Bush, and its two most recent presidential nominees, John McCain and Mitt Romney, all plan to avoid the Cleveland affair – as does Ohio’s Republican Gov. John Kasich. Shrugging off the high-profile absences, Trump’s team suggested the convention lineup would help highlight Trump’s outsider appeal.“We are totally over-booked. We have great speakers, we have winners, we have people that aren’t only political people,” Trump told Fox News Channel on Tuesday. “We have a lot of people that are just champions and winners.”The New York billionaire acknowledged in recent days that he’d be hewing a little closer to tradition.“Look, I have great respect for the institution of the conventions. I mean to me, it’s very important. So we’re not going to change the wheel,” he said on Fox.New England Patriots star quarterback Tom Brady, a Trump friend, was initially teased as a possible speaker, but will not appear on stage next week in Cleveland. Neither will former Indiana University basketball coach Bobby Knight or legendary boxing promoter Don King, a Cleveland resident and passionate Trump supporter.The program will instead feature people like pro golfer Natalie Gulbis, retired astronaut Eileen Collins, and Ultimate Fighting Championship president Dana White. In addition to the Benghazi survivors, former Navy SEAL Marcus Luttrell, author of the book, “Lone Survivor,” will make an appearance, along with Wisconsin Sheriff David Clarke, a vocal critic of the Black Lives Matter movement.The convention will also highlight religious leaders such as Jerry Falwell Jr., son of the famed televangelist, and Haskel Lookstein, the New York rabbi who converted Trump’s daughter, Ivanka to Judaism.Trump does not forget his business relationships, giving speaking slots to real estate investor Tom Barrack, PayPal co-founder Peter Thiel and even the general manager for Virginia’s Trump Winery, Kerry Woolard.And in a nod toward party unity, Trump will feature several former presidential competitors, including Cruz, Wisconsin Gov. Scott Walker, Ben Carson and Arkansas Gov. Mike Huckabee.Two finalists in Trump’s search for a running mate made the list as well: New Jersey Gov. Chris Christie and Newt Gingrich. The other finalist, Indiana Gov. Mike Pence, was not included in the program obtained by the AP.Trump had already announced that his children would be speaking, along with his wife Melania, whom he said was already working on remarks.Ivanka Trump, who along with Trump’s other adult children, has been playing an increasingly central role in the campaign, predicted in a recent radio interview the GOP convention would be “a convention unlike any we’ve ever seen.”“It will be substantive. It will be interesting. It will be different. It’s not going to be a ho-hum lineup of, you know, the typical politicians,” she said. Do you see a typo or an error? Let us know. SHAREcenter_img Author: Associated Press Published: July 14, 2016 5:29 AM EDT Updated: July 14, 2016 1:22 PM EDT last_img read more

Collabro to release new album Love Like This in November

first_imgMusical theatre group Collabro will release new album Love Like This on 15th November 2019 through BMG.Available for pre-order now, Love Like This is the group’s fifth studio album. It will be supported by an extensive tour in October 2020.Love Like This is a collection of the group’s favourite contemporary songs. The first track to be lifted from the album is a cover of Coldplay’s Fix You, which is available to stream and download now.Other tracks on the record include Keane’s Somewhere Only We Know, Ellie Goulding’s Love Me Like You Do and Lewis Capaldi’s Someone You Loved.Collabro – comprised of Michael Auger, Jamie Lambert, Matthew Pagan and Thomas J Redgave – rose to fame on Britain’s Got Talent in 2014 where they won and scored a number one album Stars in the months after.The band has enjoyed four sell-out UK tours, two US tours, headline slots at the London Palladium, Wembley Stadium, the Royal Albert Hall, the 02 Arena and a show for Her Majesty The Queen.Credit: BMGThe track listing for Love Like This is:1. Shallow2. Someone You Loved3. My Heart Will Go On4. Fix You5. A Million Dreams6. Perfect7. Only Love Can Hurt Like This8. I Can’t Help Falling in Love with You9. Love Me Like You Do10. Somewhere Only We Know11. HeroYou can see Collabro on tour in October 2020 at the following dates:Friday 2nd – Aylesbury Waterside TheatreSaturday 3rd – Southend Cliffs PavilionSunday 4th – Bexhill De La Warr PavilionTuesday 6th – Nottingham Royal Concert HallWeds 7th – Leicester De Montfort HallFriday 9th – Bournemouth ICSaturday 10th – Cardiff ArenaSunday 11th – Torquay Princess TheatreMonday 12th – Ipswich RegentWeds 14th – Bath ForumThursday 15th – Sheffield City HallFriday 16th – Llandudno Venue Cymru TheatreSaturday 17th – Hull Bonus ArenaTuesday 20th – Liverpool PhilharmonicWeds 21st – Gateshead SageFriday 23rd – Blackpool Opera HouseSaturday 24th – Harrogate Convention CentreSunday 25th – Salford LowryMonday 26th – Glasgow Royal Concert HallWeds 28th – Birmingham SymphonyThursday 29th – London PalladiumFriday 30th – Guildford G LiveSaturday 31st – Carlisle Sands Centre (+ matinee option)Tickets are on sale from Friday 13th September 2019 at https://www.gigsandtours.com/tour/collabro/.last_img read more

Don’t lose the merry from Christmas

first_imgDon’t lose the merry from ChristmasIt’s rapidly approaching Christmas Day. People are greeting each other with wishes for a “Merry Christmas,” instead of the customary “Have a nice day.” Noticeably, the genre of music played on the radio has changed to seasonal music with songs also wishing audiences a Merry Christmas.However, this year to hear people speak, you listen to electronic media, read newspapers and follow social media, it’s obvious that several hovering factors are about to steal the merry out of Christmas.Another factor is the post general election disappointment that continues to affect sections of the community. Not only are several residents disappointed that Hillary Clinton isn’t the President-elect, others are fearful, uncertain of what the future holds for them. Like first-lady Michelle Obama said in a recent interview, some people are having little reason to hope.However, to those who are finding it difficult to be merry because of the election results, they should remember that the American Constitution provide various checks and balances. These protect the rights of all residents, including immigrants, from abuses by the governing administration. America did not relinquish its fundamentals as a Democracy on November 8. It’s important for all citizens to be aware of their rights and the channels, including through those elected to represent them in the nation’s Congress, to protect these rights. What the uncertain future requires is faith and strength, not fear and cowardice. The election results shouldn’t be a reason for people to be denied enjoying a merry Christmas.Meanwhile, others are very disturbed by the televised images   of the suffering and carnage being wreaked on the people of the town of Aleppo in Syria. It twists the hearts of caring folks to see and hear  children crying, as bombs and gunshots explod around them, appealing to the world to rescue them. No doubt this is a grave tragedy, and it has led some to question why the US doesn’t have troops in Syria to prevent the blood bath that’s taking place there.However, if the US had thousands of troops fighting in Syria, the nation would again be at war, losing mostly its young people in battle. Americans  suffered through the devastating news and images of what war did to the nation’s young men and women in previous wars in Viet Nam, Iraq and  Afghanistan. Thus, people should understand why President Obama was hesitant about sending  troops into Syria. This would have risked a protracted war with Syria and its allies, including Russia. The images out of Aleppo are heart wrenching, and one hopes the United Nations can broker a satisfactory solution. However, if America was involved in the Syrian civil war, there’s little doubt the cries for American troops to pull out would be loud and persistent. Understandably, the images from Aleppo trouble some people, but this should prompt earnest prayers for a quick solution and ultimate peace, as Americans celebrate Christmas in the religious spirt in which it’s meant to be celebrated.Others say they find it difficult to be merry this Christmas as they receive persistent reports of violent crime, including domestic violence against children and women, in their American neighborhoods, and in the Caribbean. But crime is another factor that people cannot afford to cower from. Crime is a very unpleasant component of the villages we call our communities. These villages have to stand bravely, and support the authorities, including law enforcement, in combatting this scourge. We must be our brother’s keeper in the fight against crime and usual associate, poverty. It’s far from being an easy task, but one of the gifts people should grasp from Christmas this year is the gift of determination to combat crime of all sorts. Crime shouldn’t get the better of the community and, along with robbing material wealth and lives, also rob the community’s joy.There are several other factors including; persistent illnesses, financial challenges, loss of loved ones, failed relationships, that may threaten to rob some people of the merry in Christmas. However, what Christmas brings for most people is the support and fellowship of family. Being a member of a close family unit especially at an iconic religious commemoration like Christmas usually serve counter to the factors that threaten to rob people of their joy, or take the merry out of Christmas.There are usually common antidotes to the threats  which take the merry from Christmas, and joys from life. These antidotes are, strength, courage, and faith.This Christmas along with peace and love,  the National Weekly would like to wish our readers and advertisers strength, courage and faith, and yes, Merry Christmas.last_img read more